Definition of tyrosinase in English:

tyrosinase

noun

mass nounBiochemistry
  • A copper-containing enzyme which catalyses the formation of quinones from phenols and polyphenols (e.g. melanin from tyrosine).

    • ‘However, during infection and damage phenols and oxidases, such as peroxidase and tyrosinase, become decompartmentalized and could oxidize phenolic compounds to form antimicrobial quinones.’
    • ‘It is an incurable congenital condition, due in its total form to absence of the enzyme tyrosinase, which is required for melanin to be synthesized in specialized cells - the melanocytes.’
    • ‘Copper functions in many enzyme systems, such as lysyl oxidase, ceruloplasmin, cytochrome oxidase, tyrosinase, and Superoxide dismutase.’
    • ‘The copper-containing enzyme tyrosinase catalyzes the rate-limiting step in melanogenesis.’
    • ‘In this issue, Boyle et all demonstrate that commercially available antibodies against tyrosinase and glycoprotein 100 can serve as excellent immunocytochemical tools for the diagnosis of melanoma in its different variants.’

Origin

Late 19th century: from tyrosine + -ase.

Pronunciation

tyrosinase

/ˈtʌɪrəsɪneɪz//tʌɪˈrɒsɪneɪz/