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[mass noun] A copper-containing enzyme which catalyses the formation of quinones from phenols and polyphenols (e.g. melanin from tyrosine).
- ‘The copper-containing enzyme tyrosinase catalyzes the rate-limiting step in melanogenesis.’
- ‘It is an incurable congenital condition, due in its total form to absence of the enzyme tyrosinase, which is required for melanin to be synthesized in specialized cells - the melanocytes.’
- ‘In this issue, Boyle et all demonstrate that commercially available antibodies against tyrosinase and glycoprotein 100 can serve as excellent immunocytochemical tools for the diagnosis of melanoma in its different variants.’
- ‘Copper functions in many enzyme systems, such as lysyl oxidase, ceruloplasmin, cytochrome oxidase, tyrosinase, and Superoxide dismutase.’
- ‘However, during infection and damage phenols and oxidases, such as peroxidase and tyrosinase, become decompartmentalized and could oxidize phenolic compounds to form antimicrobial quinones.’
Late 19th century: from tyrosine + -ase.
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