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A synthetic antibiotic used to treat malaria and respiratory and urinary infections (usually in conjunction with a sulphonamide).
- ‘Medicines used are sulfonamide with or without trimethoprim, furadantin, ampicillin, or the fluoroquinolones.’
- ‘Certain medicines, such as some antiepileptic drugs and the antibiotic drug trimethoprim, can interfere with folate levels.’
- ‘At the same time we would also audit the prescribing of trimethoprim for urinary tract infections and the investigations and second visits associated with its use.’
- ‘For urinary tract infection, we examined resistance to ampicillin or amoxicillin and trimethoprim.’
- ‘The most commonly applied antibiotics were doxycycline, erythromycin, and trimethoprim in combination with sulfamethoxazole, which are all considered broad-spectrum antibiotics.’
1960s: from trimeth(yl) + o(xy-) + p(y)rim(idine).
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The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.