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A cell which bears receptors for a hormone, drug, or other signalling molecule, or is the focus of contact by a virus, phagocyte, nerve fibre, etc.
- ‘Interaction with the receptor of the target cell may be essential for this conformational change and the conformation itself.’
- ‘In this model, electrostatic interactions between the virus, target cell, and charged polymers determine the nature and magnitude of the driving force for virus adsorption.’
- ‘When the hormone reaches its target cell, it locks onto the cell's specific receptors and these hormone-receptor combinations transmit chemical instructions to the inner workings of the cell.’
- ‘Recombinant retroviruses are a widely used gene therapy vector because of their ability to permanently integrate a therapeutic transgene into the genome of a target cell.’
- ‘Most commonly, the steroids affect DNA transcription and the production of other molecules that are more immediately responsible for influencing the activity of the target cell.’
An abnormal form of red blood cell which appears as a dark ring surrounding a dark central spot, typical of certain kinds of anaemia.
- ‘The lack of pulsation in the middle of a target cell as opposed to a healthy specimen is due to the fact that the cell membrane has collapsed on itself.’
- ‘The second model is based on a stem cell hierarchical framework in which the target cell is a cancer stem cell that may give rise to cells capable of reinitiating the tumor and cells that have limited capacity to differentiate.’
- ‘The history of knowledge regarding the spherocyte and the target cell together with the theories of their pathogenic significance are reviewed.’
- ‘The more common episomal pattern appears as a dense, opaque, blue oval that overlies the majority of the central portion of the target cell.’
- ‘However, if the sickle hemoglobin S is combined with the target cell, some mild to moderate anemia may occur.’
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