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[mass noun] A synthetic drug used to treat breast cancer and infertility in women. It acts as an oestrogen antagonist.
- ‘About half in each of these groups were treated with chemotherapy followed by five years of tamoxifen.’
- ‘As with all medicines, tamoxifen has side effects that may affect some women and not others.’
- ‘These treatments may involve drugs such as tamoxifen, which are meant to prevent the cancer from growing again.’
- ‘‘But greater use of tamoxifen has had a huge impact over the past 10 years,’ he added.’
- ‘We do not know if raloxifene is better than tamoxifen.’
- ‘In addition to the initial therapy, most patients received tamoxifen in a dosage of 20 mg daily as adjuvant treatment.’
- ‘As this history is often incomplete, our measured population of all patients on tamoxifen is grossly underestimated.’
- ‘What are the findings from the third study, which examines switching to an aromatase inhibitor after two to three years of tamoxifen?’
- ‘However, personal history, such as abnormal biopsy, was highly correlated with the decision to take tamoxifen.’
- ‘The risk did not decrease after discontinuation of tamoxifen and was not modified by other risk factors for endometrial cancer.’
- ‘The risk is small compared to the benefits of using tamoxifen to treat breast cancer.’
- ‘The authors suggest that tamoxifen may be underused in selected groups of women who could benefit from prophylaxis.’
- ‘The question of how long patients should continue taking the drug is important because tamoxifen is not problem free.’
- ‘Patients managed as outpatients (such as those treated with tamoxifen only) were likely to be missed.’
- ‘This crystalline retinopathy is rarely seen with standard doses of tamoxifen, but when present it can cause a substantial progressive drop in visual acuity.’
- ‘Cataract surgery was required approximately twice as often among women who took tamoxifen.’
- ‘The effect found for tamoxifen also reduced the overall incidence of osteoporotic fractures of the hip, spine and radius by 19%.’
- ‘Current treatment commonly centres on tamoxifen, another drug which shrinks tumours.’
- ‘This patient's doctor may be able to get her free tamoxifen.’
- ‘As a preventive measure, taking tamoxifen doesn't guarantee that you'll remain cancer-free.’
1970s: an arbitrary formation based on trans-, amine, oxy-, phenol, elements of the drug's chemical name.
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