Which Joe gave his name to ‘sloppy joes’? We look at five interesting sandwiches and their lexical origins.
[mass noun] A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
- ‘The pharmacologic characteristics and side effects of tacrine make it a second-line agent.’
- ‘The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring.’
- ‘These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease.’
- ‘There have been no direct comparison studies to tacrine or donepezil.’
- ‘Monitoring of serum transaminase levels is recommended with use of tacrine because of potential hepatotoxicity.’
1960s: from t(etra-) + acr(id)ine.
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Before you run for the hills, let’s run through a list of ‘run’ expressions that are running through our minds.
The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.