Which Joe gave his name to ‘sloppy joes’? We look at five interesting sandwiches and their lexical origins.
Rapidly diminishing response to successive doses of a drug, rendering it less effective. The effect is common with drugs acting on the nervous system.
- ‘This spirometric improvement was maintained throughout the 13-week period without any evidence of tachyphylaxis.’
- ‘Topical steroids should be applied no more than twice a day; more frequent use provides no advantage and may induce tachyphylaxis.’
- ‘Giving methotrexate concurrently, however, suppressed tachyphylaxis, probably by preventing the production of human antichimeric antibodies.’
- ‘Trebling doses of histamine diphosphate were chosen instead of the usual doubling dose because of the half-life of lidocaine, the number of challenges, and the need to minimize possible tachyphylaxis of the histamine effect.’
- ‘The efficacy of calcipotriene is comparable to mid-potency topical corticosteroids; however, it does not cause skin atrophy or tachyphylaxis.’
We take a look at several popular, though confusing, punctuation marks.
From Afghanistan to Zimbabwe, discover surprising and intriguing language facts from around the globe.
The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.