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nounmass nounPhysiology Medicine
The union or fusion of adjacent bones by the growth of bony substance, either as a normal process during growth or as the result of ankylosis.
- ‘There may be partial or complete fusion of a suture, but a short segment of synostosis often produces the same deformity as a complete fusion.’
- ‘The clinical features include misshapen skull caused by coronal suture synostosis, wide-set eyes, midface hypoplasia, choanal stenosis, and shallow orbits.’
- ‘Familial nonsyndromic craniosynostosis, which affects 2 to 6 percent of infants with sagittal synostosis and 8 to 14 percent of infants with coronal synostosis, is transmitted as an autosomal dominant disorder.’
- ‘The calvarial shape is characteristic for each type of sutural synostosis.’
- ‘Isolated sagittal synostosis, premature fusion of the sagittal suture, is the most common type of craniosynostosis and accounts for 56% to 58% of reported cases.’
Mid 19th century: from syn- ‘together’ + Greek osteon ‘bone’ + -osis.
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