Definition of synostosis in English:



mass nounPhysiology Medicine
  • The union or fusion of adjacent bones by the growth of bony substance, either as a normal process during growth or as the result of ankylosis.

    • ‘There may be partial or complete fusion of a suture, but a short segment of synostosis often produces the same deformity as a complete fusion.’
    • ‘The clinical features include misshapen skull caused by coronal suture synostosis, wide-set eyes, midface hypoplasia, choanal stenosis, and shallow orbits.’
    • ‘The calvarial shape is characteristic for each type of sutural synostosis.’
    • ‘Familial nonsyndromic craniosynostosis, which affects 2 to 6 percent of infants with sagittal synostosis and 8 to 14 percent of infants with coronal synostosis, is transmitted as an autosomal dominant disorder.’
    • ‘Isolated sagittal synostosis, premature fusion of the sagittal suture, is the most common type of craniosynostosis and accounts for 56% to 58% of reported cases.’


Mid 19th century: from syn- ‘together’ + Greek osteon ‘bone’ + -osis.