Definition of sympatholytic in English:



  • (of a drug) antagonistic to or inhibiting the transmission of nerve impulses in the sympathetic nervous system.

    • ‘The decrease in the pulse is believed due to a sympatholytic action of MAOIs.’
    • ‘Taurine, a sulfur-containing amino acid, has been reported to have antihypertensive and sympatholytic activity.’
    • ‘These authors feel that, at the present time, the evidence seems insufficient to support the use of peripheral sympatholytic procedures in the routine management of pain.’
    • ‘Symptoms associated with this syndrome may be worsened in patients who are receiving sympatholytic agents such as clonidine (Catapres).’
    • ‘Constipation, nausea and gastric upset are also associated with the sympatholytic effects of these drugs.’


  • A drug having a sympatholytic effect, often used in the treatment of high blood pressure.

    • ‘Of the sympatholytics, prazosin and propranolol have been the subject of recent studies.’
    • ‘Thus, sympatholytics interfere with the part of the nervous system that uses norepinephrine to raise blood pressure.’
    • ‘Centrally acting sympatholytics block sympathetic activity by binding to and activating alpha 2 adrenoceptors.’
    • ‘A more complete list of sympatholytics and their trade names can be found on p.123 of the Yagiela text.’
    • ‘Clonidine is a central sympatholytic.’