Definition of sulphonamide in English:

sulphonamide

(also sulfonamide)

noun

Medicine
  • Any of a class of synthetic drugs, derived from sulphanilamide, which are able to prevent the multiplication of some pathogenic bacteria.

    • ‘Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.’
    • ‘Patients who have aspirin-sensitive asthma, or allergic reactions to aspirin or other arthritis medicines or certain sulfa drugs called sulfonamides, or who are in their third trimester of pregnancy should not take Celebrex.’
    • ‘Salicylates, nonsteroidal anti-inflammatory drugs, barbiturates, tetracycline, and sulfonamides are among the drugs most commonly cited as causes of fixed drug reactions.’
    • ‘The authors did not mention whether additional therapy could be used or how acute relapse was managed, although they prohibited patients from using antibiotics, sulfonamides, or steroids at entry to the study.’
    • ‘This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin.’

Origin

Late 19th century: from sulphone + amide.

Pronunciation

sulphonamide

/sʌlˈfɒnəmʌɪd/