Definition of squalamine in English:



mass nounBiochemistry
  • A compound of the steroid type found in sharks, which has antibiotic properties.

    • ‘In 1992, he discovered squalamine - a natural steroid that fights cancer by blocking off blood flow to tumours - in the liver of the dogfish shark.’
    • ‘While they have no proof, the researchers think squalamine is also found in other species of shark.’
    • ‘There has been no proof in clinical trials that squalamine has benefits in the in vivo setting.’
    • ‘I look forward to participating in the further development of squalamine for the treatment of lung cancer.’
    • ‘Histological analysis of eyes treated with squalamine showed a tumor with greatly diminished vascularity when compared to corresponding control sections.’


1990s: from Latin squalus (denoting a kind of marine fish and used as a rare term in English for ‘shark’) + amine.