Definition of senile plaque in English:

senile plaque

noun

Medicine
  • A microscopic mass of fragmented and decaying nerve terminals around an amyloid core, numbers of which occur in the brains of people with Alzheimer's disease.

    • ‘A team from the University of Western Australia found that deposits known as senile plaques seen in the brains of Alzheimer's patients were composed of a new type of protein, which they called beta amyloid.’
    • ‘Persons with Alzheimer's have been found to experience increased absorption of aluminum in the brain, as well as exhibit densities of senile plaques and neurofibrillary tangles.’
    • ‘The vaccine induces an immune response specifically against beta-amyloid (the protein that makes up senile plaques in Alzheimer's) and has been shown to reduce and prevent plaque formation in mice.’
    • ‘Scientists have linked Alzheimer's to a build-up of the protein, sometimes called senile plaque, in the brain.’
    • ‘Several types of senile plaques have also been found in the brains of Alzheimer's disease patients, including diffuse, neuritic, and burned out plaques.’