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A toxic crystalline compound present in santonica and related plants, used as an anthelmintic.
Chemical formula: C₁₅H₁₈O₃
‘Tenulin and helenalin were obtained from Helenium amarum, whereas santonin was commercially supplied (Sigma) and isoalantolactone was purified from helenin (Sigma) as in Dupuis et al..’
‘However, we reported in a previous study that santonin, a eudesmanolide sesquiterpene lactone, exerts no effects on the differentiation of leukemia cells.’