Definition of renin in English:



mass nounBiochemistry
  • An enzyme secreted by and stored in the kidneys which promotes the production of the protein angiotensin.

    • ‘By causing volume and sodium depletion, thiazide diuretics stimulate the production of renin and angiotensin.’
    • ‘Angiotensinogen, the initial substrate of the renin-angiotensin-aldosterone system, is produced in the liver; renin converts it to angiotensin I in the kidneys.’
    • ‘By regulating salt levels through production of an enzyme called renin (as well as other substances), the kidneys ensure that blood pressure is regulated.’
    • ‘All these changes act directly or indirectly as stimuli for the release of the enzyme renin in the kidneys, triggering a sequence of chemical events in the blood of which the end product is angiotensin II.’
    • ‘The greatest cause is probably due to lower production of hormones such as renin, angiotensin and aldosterone, caused by the increased stress (these hormones assist the body in retaining fluid).’


Late 19th century: from Latin ren ‘kidney’ + -in.