Definition of rechallenge in English:

rechallenge

noun

  • 1A challenge made in return; a second or repeated challenge.

  • 2Immunology and Medicine. The action of rechallenge; an instance of this.

verb

  • 1with object To challenge again.

  • 2with object Immunology and Medicine. To treat (a patient or animal) again with a particular infectious agent, antigen, or drug, in order to test for immunity, hypersensitivity, or other type of (often adverse) reaction.

Origin

Early 18th century; earliest use found in Francis Bugg (1640–1727), Quaker apostate. From re- + challenge<br>early 18th century. From re- + challenge. Compare rechallenge.

Pronunciation

rechallenge

/rɪˈtʃalɪn(d)ʒ/