Definition of reading frame in English:

reading frame


  • The grouping of three successive bases in a sequence of DNA that constitutes the codons for the amino acids encoded by the DNA.

    • ‘The open reading frames of all gene sequences identified were interrupted by introns.’
    • ‘Analysis of the nucleotide sequence identifies an open reading frame of 1882 codons, interrupted by one putative intron.’
    • ‘The alignment exhibited an insertion of 11 consecutive codons after the first 2 codons in the reading frame of the S gene.’
    • ‘Proteins encoded in overlapping reading frames from the same nucleotides have different levels of amino acid variation.’
    • ‘The leader transcript contains an open reading frame which encodes a polypeptide of 44 amino acids.’