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A bitter crystalline compound present in cinchona bark, used as a tonic and formerly as an antimalarial drug.
- ‘The stereochemistry of quinine is formidable: it has four chiral centres, and thus 16 stereoisomers - of which only one is the natural ingredient of cinchona bark.’
- ‘I believe at that time we were taking a variant of quinine called mepacrine, a little yellow pill which turned us a delicate shade of buttercup, and when we went on leave our friends and relatives thought we had jaundice.’
- ‘Doctors treat malaria by using anti-malarial drugs, such as chloroquine or quinine.’
- ‘One doctor told me to drink tonic water for its quinine, but it doesn't seem to help.’
- ‘In 1820, the single chemical quinine was isolated from the bark.’
- ‘My doctor prescribed quinine, which for me is a sure-fire solution.’
- ‘One of the gold standard therapies for a long time was a drug called quinine, and that was a medication that was used for prophylaxis against malaria.’
- ‘Medical breakthroughs, including sulfa drugs, penicillin, and quinine, were also a consequence of the war.’
- ‘Other important alkaloids are caffeine, ricinine, and quinine.’
- ‘Some people drink tonic water with quinine to get the drug without the prescription.’
- ‘I was drinking large quantities of tonic water, which contains quinine, when this started.’
- ‘Whether artemisinins given by any route should be replacing quinine as the initial treatment of choice for severe malaria in Africa remains an open question.’
- ‘But quinine may not be the best antimalarial treatment.’
- ‘He was treated with intravenous doxycycline in a dosage of 100 mg twice daily and oral quinine in a dosage of 650 mg twice daily for three days.’
- ‘The two most important groups of drugs for malaria treatment are still based on quinine or artemisinin.’
- ‘The patient was treated with quinine sulfate and tetracycline for 7 days.’
- ‘Her treatment was changed to intravenous quinine 600 mg every 12 hours, and she was transferred to the local intensive care unit.’
- ‘The cinchona tree contains more than 20 alkaloids of which quinine and quinidine are the most important.’
- ‘For many years the treatment of malaria in Africa has relied on chloroquine, sulfadoxine combined with pyrimethamine, and quinine, with the latter being used mainly to treat severe cases.’
Early 19th century: from Spanish quina ‘cinchona bark’ (from Quechua kina ‘bark’) + -ine.
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