Definition of prozone in English:

prozone

noun

Medicine
  • [mass noun] (in testing for antigens) the range of relative quantities of precipitin (or agglutinin) and antigen within which any precipitation (or agglutination) is inhibited by the predominance of one component.

    • ‘In addition, these tests may show a ‘prozone’ phenomenon in which large amounts of antibody block the antibody-antigen reaction, causing a false-negative test in the undiluted sample.’
    • ‘However, highly concentrated antibodies may result in a prozone effect, leading to decreased intensity of staining.’

Origin

Early 20th century: from pro- before + (agglutination) zone.

Pronunciation:

prozone

/ˈprəʊzəʊn/