Definition of prostate-specific antigen in English:

prostate-specific antigen

(also PSA)


mass nounMedicine
  • An antigenic enzyme released in the prostate and found in abnormally high concentrations in the blood of men with prostate cancer.

    • ‘Men middle-aged and older routinely get blood tests for prostate-specific antigen, or PSA, to screen for prostate cancer.’
    • ‘The American Urological Association has released a policy report on the use of prostate-specific antigen in screening for and monitoring of prostate cancer.’
    • ‘Assays are now available that can measure very low concentrations of prostate-specific antigen, but their analytic performance and clinical utility are not well defined.’
    • ‘In light of the urinary symptoms, he then had his blood tested for prostate-specific antigen, a protein elevated in prostate cancer.’
    • ‘The treatment also increases blood concentrations of prostate-specific antigen, or PSA, a marker associated with prostate cancer and prostate enlargement.’