Definition of prochlorperazine in English:



mass nounMedicine
  • A synthetic compound derived from phenothiazine, used as a tranquillizer.

    • ‘The most effective medications at this time appear to be prochlorperazine, chlorpromazine and sumatriptan, each having a pain-relief efficacy in acute migraine of greater than 70 percent.’
    • ‘The phenothiazines prochlorperazine and chlorpromazine have been shown to reduce nausea and vomiting of pregnancy compared with placebo.’
    • ‘Besides ergotamine and prochlorperazine, very few migraine-specific medications are available in suppository form.’
    • ‘Alternative PRN antiemetics (e.g., prochlorperazine, lorazepam, metoclopramide) are a more rational choice as an adjunct to properly scheduled granisetron or ondansetron.’
    • ‘Several antiemetics, such as metoclopramide, chlorpromazine, prochlorperazine, and promethazine, are regarded as safe for use during pregnancy.’


1950s: from pro(pyl) + chlor(ine) + (pi)perazine.