One of the mysteries of the English language finally explained.
Originally (more fully "porokeratosis of Mibelli"): an inherited (autosomal dominant) disorder of the skin characterized by the presence of annular lesions with raised horny borders surrounding atrophic centres. Later also: a skin lesion of this kind; (with distinguishing word or words) any of several other inherited or acquired skin disorders characterized by the presence of similar lesions.
Late 19th century. From poro- + keratosis, after Italian porocheratosi.
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