Definition of plasmin in English:



mass nounBiochemistry
  • An enzyme, formed in the blood in some circumstances, which destroys blood clots by attacking fibrin.

    • ‘Degradation of fibrin clots is the function of plasmin, a serine protease that circulates as the inactive proenzyme, plasminogen.’
    • ‘The fibrinolytic system involves a series of enzymatic reactions that results in the conversion of the proenzyme, plasminogen, into the trypsin-like lyric enzyme, plasmin.’
    • ‘The broad spectrum serine protease plasmin is formed following cleavage of the zymogen precursor plasminogen by host activators tissue plasminogen activator and urokinase.’
    • ‘Substitution of Glu 351 also altered the specificity toward non-cognate proteases: plasmin and thrombin.’
    • ‘Plasminogen activators attached to fibrin activate plasminogen, causing the release of the enzyme plasmin within clots and thrombi.’


Mid 19th century: from French plasmine, from late Latin plasma ‘mould, image’.