Definition of pathological in English:

pathological

(North American pathologic)

adjective

  • 1Relating to pathology:

    ‘the interpretation of pathological studies’
    • ‘In past studies, significant pathologic findings were not found in 3 to 82 percent of such patients.’
    • ‘More detailed prospective clinical and pathologic studies may assist in clarifying the etiology and pathogenesis of these disorders.’
    • ‘Clinical and pathologic data for the 84 patients studied are shown in Table 1.’
    • ‘The pathological mechanisms of disease progression are unclear but oxidant stress may play a role.’
    • ‘All the cases included demonstrated clinical and pathologic evidence of ischemia after chart review.’
    • ‘Until now, there has been no pathologic study of symptomatic infants: the youngest patients biopsied previously had been 3 years old.’
    • ‘It appears from our data that a single measurement of the bronchial tree reflects the severity of disease as determined by pathologic analysis.’
    • ‘From here, he was awarded a New Zealand Fellowship to study pathological anatomy in the United States.’
    • ‘Clinical, radiographic, and pathologic findings, including ultrastructural studies in select cases, were analyzed and correlated.’
    • ‘The identified infants were included in the study when placental pathologic and cranial ultrasonographic data were available for review.’
    • ‘The clinical and key pathologic features of the cases we studied are summarized in the Table.’
    • ‘Studies looking at pathological or brain imaging data would be needed to address these possibilities.’
    • ‘The author claims that historical, iconographic, pathological, physical, and chemical evidence points to inauthenticity.’
    • ‘Our goal is to provide a framework for studying these adaptive and pathologic changes.’
    • ‘Epidemiological, clinical and pathological data from all patients treated in our institute have been recorded on a computerized database since 1996.’
    • ‘In the present study, clinical diagnoses substantially agreed with pathologic diagnoses.’
    • ‘The thing that separates boys and girls in academic ability is nothing to do with gender, or hormones, or anything physical, pathological, histological, or hormonal.’
    • ‘The clinical and pathologic findings of this study are summarized in the Table.’
    • ‘They therefore act as indicators of any recent pathological state or acute illness.’
    • ‘Microscopic images captured with digital cameras for pathologic studies have been analyzed at many research institutes.’
  • 2Involving or caused by a physical or mental disease:

    ‘glands with a pathological abnormality’
    • ‘Careful inspection of the bones revealed distinct pathologic abnormalities.’
    • ‘Forensic pathologists see the natural pathologic progression of many untreated diseases.’
    • ‘The patient continued to develop further skeletal metastases with pathological fractures and finally died ten months after the initial presentation.’
    • ‘Elevated intracranial pressure is present in many pathologic states, including meningitis, intracranial hemorrhage, and tumors.’
    • ‘Chronic wounds may result from pathologic disease processes.’
    • ‘Because of this it can also help remove the pathological buildup of calcium associated with arthritic joints.’
    • ‘No pathological abnormalities such as serious disease or physical deformities were recorded.’
    • ‘Whether these pathologic changes are associated with abnormal pulmonary function or gas exchange abnormalities awaits further study.’
    • ‘Haemorrhoids result from the pathological changes in prolapsed anal cushions.’
    • ‘The following studies are examples of pathological responses in animals that were induced by exposure to UV rays.’
    • ‘Evidence of pathological change in the COPD diaphragm is continuing to mount.’
    • ‘Forty-four patients were enrolled in the present study and the baseline pathologic and clinical characteristics of this group are summarized in Table 1.’
    • ‘We define primary bronchiolar disorders as those diseases in which an isolated pathologic process is limited to bronchioles anatomically.’
    • ‘We can see that the Egyptians recognized the connection between food and the cause of certain pathological diseases.’
    • ‘But just as a workable and testable theory has evolved, important work by an international group implies potentially four pathological patterns of multiple sclerosis.’
    • ‘Our study of pathological prognostic factors at presentation confirmed these findings for women with early breast cancer.’
    • ‘The etiology remains unclear, and the association with cardiac pathological changes is uncertain.’
    • ‘Destruction of the alveolar walls, one of the pathologic changes in pulmonary emphysema, had been considered irreversible.’
    • ‘However, 39,901 of the appendixes removed showed no pathologic features of appendicitis.’
    • ‘Animal models are widely used in the study of pathologic processes of periodontitis.’
    morbid, diseased
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  • 3informal Compulsive; obsessive:

    ‘a pathological gambler’
    • ‘But, most people with a pathological obsession with ‘race’ are not in asylums, so we must address them as a component of our everyday lives.’
    • ‘Probable pathological gamblers have a score greater than 4, and were included in the present study as problem gamblers.’
    • ‘Another limitation is that it focused on people with relatively minor gambling problems - only four of the participants were classified as pathological gamblers.’
    • ‘Psychologists and social workers define pathological gamblers as those whose gambling is persistent and out of control.’
    • ‘As indicated in the literature, probable pathological gamblers in adolescence are at risk of becoming adult pathological gamblers, especially when they participate in a variety of gambling activities.’
    • ‘Of course, America's critics regard the country's obsession with sovereignty and self-government as anachronistic and pathological.’
    • ‘A minority will continue to become pathological gamblers.’
    • ‘The essential problem with compulsive gamblers, however, is their blindness to this pathological desire to lose.’
    • ‘The same schedule is in all gambling devices and it creates the pathological gambler.’
    • ‘Because treatment tends to be individually focused, most family members of pathological gamblers never receive the care they need.’
    • ‘However, in the U.S., such decisions have increasingly become pathological obsessions, as men become more and more subject to unattainable body ideals.’
    • ‘We found that our three probable pathological gamblers usually gambled with family and close friends.’
    • ‘To understand causes of compulsive gambling or pathological gambling, it is useful to explore causes of impulse control disorders.’
    • ‘Problem gambling and pathological gambling are well-defined psychiatric conditions.’
    • ‘To check out all the other results and confirm that my pathological lying ‘issue’ is all in the past, click here and see for yourself.’
    • ‘I think that's one of the reasons that the home run derby has become such a pathological obsession over the last couple of seasons.’
    • ‘It was an obsession bordering on the pathological.’
    • ‘A score of five or more categorizes the participant as a ‘probable pathological gambler’, three or four as a ‘problem gambler’.’
    • ‘‘I do not understand your pathological obsession about mysteries,’ Chase mumbled as he followed after his dark-haired cousin.’
    • ‘I think I've indulged in a pathological, chronic nostalgia over the years, which I've traced back to my childhood.’
    compulsive, obsessive, inveterate, habitual, persistent, chronic, clinical, hardened, confirmed, unreasonable, irrational, illogical
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Pronunciation:

pathological

/paθəˈlɒdʒɪk(ə)l/