Definition of pathogenicity island in English:

pathogenicity island


  • A series of contiguous genes in a pathogenic microorganism including one or more that determines virulence, acquired by horizontal gene transfer.

    • ‘Its genetic code is embedded in a complex DNA structure called the TCP pathogenicity island.’
    • ‘The genes encoding the attaching and effacing (A / E) phenotype are situated on a 43 kb pathogenicity island.’
    • ‘The ability of EPEC to adhere to the cells and produce A / E lesions has been attributed to the genes encoded on the pathogenicity island.’
    • ‘Salmonella can sense bile in the intestine and use it as a signal to downregulate secretion and invasion genes of pathogenicity island.’
    • ‘This suggests diversity in mechanisms or specificities of pathogenicity island acquisition.’