Definition of ovariectomize in English:

ovariectomize

(also ovariectomise)

verb

[WITH OBJECT]usually as adjective ovariectomized
  • Perform surgical removal of one or both ovaries on (a woman or female animal)

    ‘regulating the endocrine system in pregnant and ovariectomized rats’
    • ‘We have shown that estrogen replacement in ovariectomized female rats attenuates blood pressure responses to psychological stress and that the non-conventional neurotransmitter, nitric oxide (NO), mediates these effects in the brain.’
    • ‘The other group of ovariectomized mice was given only purified water.’
    • ‘In contrast, Binkley et al found no benefit on bone turnover or distal femur BMD density in ovariectomized rats.’
    • ‘The U.S. Food and Drug Administration has accepted the ovariectomized (OVX) rat model as a model for studying osteoporosis; thus, most rodent experiments have employed ovariectomized animals to study the effects of soy isoflavones.’
    • ‘Postmenopausal osteoporosis, characterized by increased fracture risk, can be accurately modeled using ovariectomized animals.’
    • ‘Four groups of eight rats and mouse were ovariectomized (ovx) by electrotomy via the dorsal route in anesthesia.’
    • ‘On day 1, rats were either sham-operated or ovariectomized.’
    • ‘A randomized placebo controlled study was undertaken to evaluate the effect of ipriflavone (IP) against the bone loss in premenopausal ovariectomized women and postmenopausal women.’
    • ‘For example, stress can impair acquisition of a conditioned response in female rats (but not if ovariectomized) while the same stressor facilitates learning in males.’
    • ‘Currently it is unknown whether long-term use of red clover would have an estrogenic effect on the human female breast or endometrium, but data suggest it is weakly estrogenic in the ovariectomized rat model.’

Origin

1920s: from ovariectomy + -ize.

Pronunciation

ovariectomize

/ˌəʊvərɪˈɛktəmʌɪz/