Definition of osteogenesis imperfecta in English:

osteogenesis imperfecta

noun

Medicine
  • [mass noun] An inherited disorder characterized by extreme fragility of the bones.

    • ‘Various clinical conditions such as osteomalacia, osteoporosis, and osteogenesis imperfecta bear witness to the inadequacies of poorly formed bone in fulfilling the role of support to the human body.’
    • ‘Kwanini, who suffers from osteogenesis imperfecta (brittle bone disease), has been in a wheelchair since the age of nine.’
    • ‘Three children with severe osteogenesis imperfecta received allogeneic bone marrow transplants; in two osteoblast engraftment was shown.’
    • ‘In a recent study in Nature Medicine, normal bone marrow derived cells that were infused into patients suffering from osteogenesis imperfecta, a genetic disease.’
    • ‘For example, children with an inherited condition known as osteogenesis imperfecta have bones that are brittle and more susceptible to breaking.’

Origin

Modern Latin, from osteogenesis + Latin imperfecta imperfect (feminine of imperfectus).

Pronunciation:

osteogenesis imperfecta

/ˌɪmpəːˈfɛktə/