Definition of occlude in English:

occlude

verb

[with object]formal, technical
  • 1Stop, close up, or obstruct (an opening, orifice, or passage)

    ‘thick make-up can occlude the pores’
    • ‘Instead, the barrel pore is occluded by a large, globular amino-terminal domain, termed the plug.’
    • ‘An ascending dissection occasionally can occlude the ostium of a coronary artery and lead to myocardial infarction.’
    • ‘In earlier models of the closed nAChR channel, pore-facing side chains of leucines of the Equatorial ring almost occlude the pore.’
    • ‘All this is jam-packed into your sinuses and other nasal structures, occluding your airway completely.’
    • ‘In their study, Morgan and coworkers occluded the contralateral nostril, and the patients therefore performed a ‘gasp’ rather than a sniff.’
    • ‘Then to add totally to all my problems, my thyroid has overgrown and was occluding my throat.’
    • ‘However, these side chains do not fully occlude the pore but rather appear to form a hydrophobic barrier to ion permeation.’
    • ‘In 1882, Karl Huber reported on 17 patients with cardiac infarcts, which he attributed to occluded coronary arteries.’
    • ‘The important feature of this closed state model is that the side chains of leucines of the Equatorial ring do not occlude the pore completely.’
    • ‘Margaret's left internal carotid artery was completely occluded at its origin.’
    • ‘The prime focus in the treatment of an AMI in the 1980s and 1990s was on the re-establishment of flow in the acutely occluded coronary artery.’
    • ‘After acquiring Doppler sounds at the palmar arch, the RNFA occludes the radial artery flow.’
    • ‘Fibroid embolisation - both uterine arteries are occluded using a transfemoral approach.’
    • ‘Furthermore, this stent can be implanted without occluding the side bronchus.’
    • ‘The size of the catheter should be small enough so as not to occlude the artificial airway totally, thus avoiding excessive negative pressure.’
    • ‘In ACS, the unstable plaque ruptures, thromboses, and occludes the artery, causing angina.’
    • ‘Tumors in the tracheobronchial tree often occlude major airways producing obstructive pneumonitis and hypoxia.’
    • ‘The left middle cerebral artery was almost completely occluded by fungal emboli.’
    • ‘Cystourethroscopy showed a large bladder tumor completely occluding the right ureteric orifice.’
    • ‘Devices for occluding the urethra include urethral plugs and, more recently, expandable urethral devices.’
    chunk, hunk, brick, slab, lump, piece
    block, block up, stop, stop up, obstruct, clog, clog up, close, shut, fill, bung up, choke, seal, plug
    View synonyms
    1. 1.1 Shut in.
      ‘they were occluding the waterfront with a wall of buildings’
    2. 1.2 Cover (an eye) to prevent its use.
      ‘it is placed at eye level with one eye occluded’
      • ‘They fixated the center of the display while they occluded one eye with the ipsilateral hand.’
      • ‘He uses the finding of Wiesel and Hubel, that kittens reared with one eye occluded do not have binocular cells in the visual cortex, to support the converse of Hebb's postulate.’
  • 2no object (of a tooth) come into contact with another tooth in the opposite jaw.

    ‘in monkeys and apes, the upper canine occludes with the lower first premolar’
    • ‘This matching of the cusps allowed the teeth to occlude, or meet, in a precision bite.’
    • ‘It consists of a pair of mandibular tooth plates that occludes with two pairs of plates above.’
    • ‘The protocone and, if present, the hypocone of the upper molar occlude directly with this surface.’
    • ‘The anteriormost teeth are smaller than the more posterior ones, and the anterior upper teeth do not occlude with the anterior lower teeth.’
    • ‘Because only one tooth row can occlude at a time in goats, the bite point acts as a fulcrum.’
    • ‘The clear implication is that, at least in Idiognathodus, the teeth occluded in a regular and precise way.’
    • ‘The peglike first upper molar does not occlude with any tooth of the lower jaw, so it serves no clear function.’
    • ‘It does occlude with this tooth in what appears to be a fully functional manner, and it retains the pattern of its cusps.’
  • 3Chemistry
    (of a solid) absorb and retain (a gas or impurity)

    ‘occluded within these crystals are other molecules’
    • ‘Moreover, once bound to a target protein, the scaffold could occlude the binding of other molecules that normally interact with the protein.’
    • ‘If the pore in the closed channel is occluded sterically, such a molecule should be unable to reach substituted cysteines below the gate.’
    • ‘Could the magmatic conditions at depth allow argon to be occluded within the minerals at the time of their formation?’
    • ‘H2O molecules can be tightly bound to biological material and are occluded in proteins where they are often involved in catalytic reactions.’
    • ‘The core of the earth - 2150 miles in radius - is thought to be largely composed of iron with about 10 percent occluded hydrogen.’

Origin

Late 16th century: from Latin occludere ‘shut up’.

Pronunciation

occlude

/əˈkluːd/