Definition of Noonan syndrome in English:

Noonan syndrome

(also Noonan's syndrome)

noun

Medicine
  • An inherited (autosomal dominant) syndrome typically characterized by short stature, facial dysmorphism, webbed neck, congenital heart disease, and various other abnormalities, resembling Turner's syndrome but without sex chromosome abnormalities.

Origin

1960s. From the name of Jacqueline Anne Noonan (b. 1928), U.S. paediatrician, who first described this syndrome (with D. A. Mehnke) in 1963 ( Jrnl. Pediatrics 63 468–70) + syndrome. In β form from the genitive of Noonan + syndrome.

Pronunciation

Noonan syndrome

/ˈnuːnən ˌsɪndrəʊm/