Definition of nick translation in English:

nick translation

noun

Biochemistry
  • A process used especially to insert labelled nucleotides into a strand of DNA, in which a DNA polymerase adds new nucleotides to the strand on one side of a nick whilst removing nucleotides from the strand on the other side, thus effectively replacing a sequence of nucleotides and translating the nick some distance along the strand.

Origin

1970s; earliest use found in Chromosoma.