One of the mysteries of the English language finally explained.
- ‘It forms the neurofibrillary tangles of Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia, corticobasal degeneration, postencephalitic parkinsonism, and a handful of others.’
- ‘Molecular studies led to an understanding of the formation of extracellular plaques (flat patches) and intercellular neurofibrillary tangles, autopsy markers of Alzheimer's.’
- ‘Two microscopic changes occur in the brain in Alzheimer's disease: senile plaques develop between neurons, and neurofibrillary tangles develop within neurons.’
- ‘Among the very earliest sites of neurofibrillary pathology in Alzheimer's disease are the hippocampus and entorhinal cortex.’
- ‘Similarly, the amyloid plaques and neurofibrillary tangles that characterise Alzheimer's disease may be found at autopsy in people aged 70 years and above even if there was no clinical evidence of dementia.’
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