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[mass noun] A synthetic drug, similar to morphine, which blocks opiate receptors in the nervous system and is used chiefly in the treatment of heroin addiction.
- ‘Thus, the researchers proposed the hypothesis that alcohol releases endogenous opioids and that naltrexone blocks the opioid receptor.’
- ‘Small studies have suggested that the opiate antagonist naltrexone is effective as an adjuvant therapy for treating alcohol addiction.’
- ‘It is working on a version containing naltrexone, an opiate antagonist that would block oxycodone's euphoric effects once the pill was crushed.’
- ‘In addition, this research group also determined that naloxone, an opiate antagonist similar to naltrexone, prevented the action of both marijuana and heroin on dopamine transmission.’
- ‘The use of the opiate antagonist, naltrexone in the treatment of autism is reasonable since it antagonizes endogenous opiate receptor activity.’
- ‘Long-term opioid therapy for chronic pain or heroin dependence is a contraindication for naltrexone because the drug could precipitate severe withdrawal syndrome.’
1970s: from a contraction of N-al(lylnoroxymorph)one (see naloxone), with the insertion of the arbitrary element -trex-.
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