One of the mysteries of the English language finally explained.
A large, abnormally developed red blood cell typical of certain forms of anaemia, associated with a deficiency of folic acid or of vitamin B₁₂.
- ‘Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.’
- ‘Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.’
- ‘Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.’
- ‘Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.’
- ‘Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.’
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