Definition of low-density lipoprotein in English:

low-density lipoprotein


mass nounBiochemistry
  • A class of lipoproteins of relatively low density, the main function of which is to transport cholesterol to the tissues.

    • ‘Doctors currently measure blood concentrations of two forms of cholesterol, high-density and low-density lipoprotein (HDL and LDL), to assess risk of heart disease.’
    • ‘Not surprisingly, the responders also showed a significant reduction in serum levels of total cholesterol, low-density lipoprotein cholesterol and phospholipid after four weeks.’
    • ‘Research evaluating the benefit of therapies aimed at lowering the levels of low-density lipoprotein cholesterol and increasing the levels of HDL cholesterol is needed.’
    • ‘Several forms of familial hypercholesterolemia are the result of genetic defects in the gene encoding the receptor for low-density lipoprotein.’
    • ‘Conventional lipid-lowering treatments are underused in patients with diabetes because blood levels of cholesterol and low-density lipoprotein cholesterol tend to be within normal ranges.’