Definition of loop of Henle in English:

loop of Henle


  • The part of a kidney tubule which forms a long loop in the medulla of the kidney, from which water and salts are resorbed into the blood.

    • ‘If ion regulation fails in the proximal tubule and loop of Henle, causing elevated potassium levels, cellular membranes become excitable and cardiac fibrillation is possible; if decreased, flaccid paralysis is possible.’
    • ‘The distal straight portion of the proximal tubule is in continuity with the thin limb of the loop of Henle, which extends into the kidney medulla and returns as the thick limb to the cortex.’
    • ‘Loop diuretics (furosemide, bumetanide, torasemide) inhibit sodium and chloride reabsorption in the thick ascending loop of Henle.’
    • ‘Moreover, other biological activities have been recognized, such as its action on the thick ascending limb of the loop of Henle and its role as a neurotransmitter or neuromodulator in the nervous system.’
    • ‘Loop diuretics frusemide and bumetanide have a powerful diuretic action, increasing the excretion of sodium and water via their action on the ascending limb of the loop of Henle.’


Mid 19th century: named after Friedrich G. J. Henle (1809–85), German anatomist.


loop of Henle