One of the mysteries of the English language finally explained.
A synthetic compound used as a local anaesthetic, e.g. for dental surgery, and in treating abnormal heart rhythms.
An aromatic amide; chemical formula: C₁₄H₂₂N₂O
- ‘Patients had their throat sprayed with lignocaine before endoscopy and were also offered intravenous sedation with midazolam.’
- ‘The convulsions did not respond to phenobarbitone, phenytoin, clonazepam, lignocaine, or pyridoxine, which were tried according to our hospital's guidelines for the management of neonatal seizures.’
- ‘Other topical medicines have been used to induce vasoconstriction, including adrenaline, oxymetazoline, xylometazoline and phenylephrine, combined with lignocaine for anaesthesia.’
- ‘Local anaesthetics, for example benzocaine and lignocaine are used in both lozenges and throat sprays.’
- ‘In 1984 he was sentenced to the gas chamber for murdering 12 patients with lignocaine (lidocaine).’
- ‘Immigration officials found the prescription-only local anaesthetic, lignocaine, in a medical aid kit in his car.’
- ‘Although lignocaine has been shown to suppress mechanically induced as well as ammonia and capsacin-induced cough, it has not been shown to suppress maximum voluntary cough.’
- ‘The patient was given a dose of lignocaine, but his condition worsened.’
- ‘Patients given intrathecal methylprednisolone and lignocaine took 70% fewer analgesics in the four weeks after treatment.’
- ‘When we had more surgery to do than we had anticipated I have used lignocaine at least 10 years out of date, stored away in a hospital pharmacy in the middle of the country, without any apparent loss of its effect.’
- ‘We designed and distributed a warning poster as soon as we knew that operating theatres had been issued with that particular kind of lignocaine.’
- ‘In 1905, cocaine was replaced by the synthetic drug novocaine This in turn was replaced by lignocaine, which is in use today.’
- ‘In a double blind, randomised, placebo controlled trial, Murphy et al compared local injection of betamethasone plus lignocaine in 14 subjects with lignocaine alone in 10 control subjects.’
- ‘Shoulder tip and pelvic pain after surgery can also be decreased using lignocaine instilled subdiaphragmatically and also into the mesosalpinx (grade A evidence).’
- ‘The introduction of cardiac monitors may allow additional interventions, as full medical kits often include other drugs such as lignocaine and digoxin.’
- ‘All procedures were performed with the patient in the left lateral position, and 2% lignocaine was used as local anaesthetic.’
- ‘He highlighted the potentially deadly similarity between 5ml plastic ampoules of the clear liquids water, saline and lignocaine, a local anaesthetic.’
- ‘Twice last year the British Medical Journal gave column space to doctors reporting confusion between ampoules of water, saline, and lignocaine (also called lidocaine) for injection.’
- ‘Fortunately, in this case mistaking water for lignocaine had no serious consequences other than requiring re-injection with local anaesthetic.’
- ‘Although dental local anaesthetic injections such as lignocaine can enter the placenta, which filters out most drugs, the doses used in most dental procedures are considered safe.’
1950s: from ligno- ( Latin equivalent of xylo-, used in the earlier name xylocaine and reflecting chemical similarity to xylene) + -caine (from cocaine).
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