Definition of Lesch–Nyhan syndrome in English:

Lesch–Nyhan syndrome

noun

mass noun
  • A rare hereditary disease which affects young boys, usually causing early death. It is marked by compulsive self-mutilation of the head and hands, together with learning difficulties and involuntary muscular movements.

Origin

1960s: named after Michael Lesch (born 1939) and William L. Nyhan (born 1926), American physicians.

Pronunciation

Lesch–Nyhan syndrome

/lɛʃˈnʌɪhən/