One of the mysteries of the English language finally explained.
A mouse whose DNA has been genetically engineered so that it does not express particular proteins.
- ‘Postdoctoral fellow Deborah Burks, lead author of the Nature paper, decided to examine fertility in the knockout mice.’
- ‘Liver regeneration is impaired in iNOS gene knockout mice.’
- ‘The phenotype of a knockout mouse provides important clues about the gene's normal role.’
- ‘The knockout mice in the other cage were watched for 45 minutes (a little over 3 minutes are shown here) and no aggressive behavior was observed.’
- ‘More importantly, researchers can use knockout mice to develop better models of many inherited human diseases.’
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