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[mass noun] A substance secreted by the stomach which enables the body to absorb vitamin B12. It is a glycoprotein.
- ‘The vitamin is then bound by intrinsic factor, a protein secreted by parietal cells of the stomach, and carried to the ileum where it is absorbed.’
- ‘Without intrinsic factor, vitamin B - 12 can't be absorbed and leaves the body as waste.’
- ‘The detection of serum antibodies to intrinsic factor and an elevated serum gastrin level confirmed the diagnosis of pernicious anemia.’
- ‘Your stomach needs to secrete intrinsic factor in order to absorb B12, and if for some reason it doesn't, you will need to have regular vitamin B12 injections.’
- ‘In most cases, vitamin B12 deficiency happens because the stomach cannot produce enough of a substance called intrinsic factor, which is needed for vitamin B12 to be absorbed.’
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