One of the mysteries of the English language finally explained.
An internal segment of amino acids that is excised from a protein precursor to generate a new protein.
- ‘It encodes a bifunctional protein with two domains, a homing endonuclease and a self-splicing intein.’
- ‘Intein excision depends on the splicing domain of the intein and the first amino acid residue of the C-extein.’
- ‘The MSI group takes the molecule of interest - say, a protein ligand - and attaches an intein to it.’
- ‘Trans-splicing is a variation that occurs when the intein is split and exists on two separate protein strands.’
1990s: from internal + protein.
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