Definition of histidine in English:



mass nounBiochemistry
  • A basic amino acid which is a constituent of most proteins. It is an essential nutrient in the diet of vertebrates, and is the source from which histamine is derived in the body.

    Chemical formula: C₆H₉N₃O₂

    • ‘The amount of the amino acids threonine, proline and histidine were also increased in roots of slag-cultivated maize plants.’
    • ‘The most prevalent amino acid is cysteine with other major ones including tyrosine, histidine, lysine and arginine.’
    • ‘Amino acids like histidine and glutamic acid that readily form complexes with chromium were also shown to increase absorption.’
    • ‘Children also require two further amino acids, histidine and arginine.’
    • ‘In humans, histamine is synthesized from histidine, a conditionally-essential amino acid.’


Late 19th century: from Greek histos ‘web, tissue’ + -ide + -ine.