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Any of a group of complex lipids which are present in the grey matter of the human brain.
- ‘The condition is due to the absence of an essential enzyme that breaks down a substance called ganglioside, present mainly in the nervous system.’
- ‘We have also clarified the binding specificity of gangliosides with proteins depending on the combination of oligosaccharide chain and protein surface modification.’
- ‘The most complex of these are the gangliosides, which contain one or more sialic acid residues and thus have a net negative change under physiological conditions.’
- ‘This may be explained by the difference in interaction of the tip with the polar zwitterionic PC headgroups and the anionic oligosaccharide headgroups of the ganglioside.’
- ‘There has been strong biochemical evidence that gangliosides are concentrated in these structures.’
1940s: from ganglion + -oside (see -ose, -ide).
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