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[mass noun] An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.
- ‘In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.’
- ‘Each microvillus contains a core of actin filaments organized in bundles by actin binding proteins such as villin, fibrin, and espin.’
- ‘All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis.’
- ‘Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.’
- ‘It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.’
Early 19th century: from fibre + -in.
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