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Remove the nucleus from (a cell):‘replication will occur in enucleated cells’
- ‘The fact that erythrocyte size correlates positively with genome size in mammals, even though their mature red blood cells are enucleated, strongly supports this hypothesis.’
- ‘They took the eggs from donor sheep and removed the nuclei from them, creating enucleated eggs.’
- ‘Having found that cumulus cells yielded better results, unfertilised mouse eggs were enucleated and their donor's nuclei put in place.’
- ‘DNA from human skin cells were placed within enucleated human embryos and then exposed to chemical and growth factors.’
- ‘An egg cell is enucleated, that is, the nucleus is removed and replaced with the nucleus from the body cell of an animal of the same kind.’
2Surgically remove (a tumour or gland, or the eyeball) intact from its surrounding capsule:‘when an eyeball is enucleated, as much of the optic nerve as possible should be removed’
- ‘All other tumors were enucleated and no recurrence was encountered.’
- ‘The blind left eye was enucleated in January 2001 to help establish the diagnosis and showed a mass lesion involving the vitreous cavity and with a mild thickening of the choroid.’
- ‘Once freed, the tumor is enucleated through the incision using the curette.’
- ‘The prostates were subsequently enucleated or removed and examined by a pathologist.’
- ‘The tumor recurred 1 year later and was enucleated again at the local hospital.’
(of a cell) lacking a nucleus.
- ‘These small, enucleate cells are produced from large parent cells, the megakaryocytes, in the bone marrow.’
- ‘Erythrocytes are enucleate and contain primarily globin mRNA.’
- ‘There were no obviously enucleate cells, no apoptotic bodies, and no evidence of dead crushed cells (data not shown).’
- ‘Tapetal cells have a very short life span and for the most part are fully functional while being enucleate.’
- ‘The results strongly suggest that some mRNA species are imported into sieve elements, which are enucleate, from neighbouring companion cells.’
Mid 16th century (in the sense ‘clarify, explain’): from Latin enucleat- extracted, made clear, from the verb enucleare, from e- (variant of ex-) out of + nucleus kernel (see nucleus).
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