Definition of disulphide in English:


(also disulfide)


  • 1A sulphide containing two atoms of sulphur in its molecule or empirical formula.

    ‘molybdenum disulphide’
    • ‘Solid lubricants such as soap, molybdenum disulphide or graphite are preferred to mineral oils and greases.’
    • ‘The finish contains molybdenum disulfide, making for a very slick, smooth finish.’
    • ‘Molybdenum disulfide is all the rage in rifles right now.’
    • ‘Phosphorothioate modification was obtained using tetraethylthiuram disulfide for 15 min at room temperature as recommended by Applied Biosystems.’
    • ‘Toxicology experts testified that the animals had succumbed to carbon disulfide poisoning.’
    1. 1.1An organic compound containing the group —S—S— bonded to other groups.
      [as modifier] ‘disulphide bonds’
      • ‘The connectivity of the disulfide linkages is not known.’
      • ‘At 50 mM reductant, some disulfide formation remains as revealed by the persistent dimer band.’
      • ‘The native structure of lysozyme contains both a-helical and beta-sheet domains, including four disulfide bonds.’
      • ‘When cysteine mutations are performed on the participating residues, spontaneous disulfide bond formation is observed.’
      • ‘One mutation, C282Y, disrupts an intramolecular disulfide bridge and renders the protein nonfunctional.’
      • ‘Disulfide bond formation is a common consequence of oxidative stress in cellular proteins.’