One of the mysteries of the English language finally explained.
A synthetic compound used in the treatment of alcoholics to make drinking alcohol produce unpleasant after-effects.
Alternative name: tetraethylthiuram sulphide; chemical formula: (C₂H₅)₂NCSSCN(C₂H₅)₂Also called Antabuse (a trademark)
- ‘Occasionally the modestly toxic disulfiram (Antabuse ®) is useful.’
- ‘The rationale for disulfiram in treating alcoholism is that most alcoholics taking disulfiram will not drink for fear of getting sick.’
- ‘Consuming alcohol after taking disulfiram results in symptoms such as palpitations, flushing, nausea, vomiting, and headache.’
- ‘Outcomes of patients who take disulfiram are improved when the drug is taken under supervision.’
- ‘I inform my alcohol-dependent patients that disulfiram, at a nickel per pill, may be viewed as inexpensive.’
1940s: blend of disulfide (see disulphide) and thiuram (from thio- + urea + amide).
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