Definition of derange in English:



[with object]
  • 1Make (someone) insane.

    ‘that business last month must have deranged him a bit’
    • ‘No wonder I am deranged and will probably have to spend a big portion of my adult earnings in therapy.’
    • ‘Imagine going home to your family and friends and being told you were deranged!’
    • ‘However, there is a distinct possibility that I am slightly deranged, so it could just be me that looks at life that way.’
    • ‘Maybe it's just some psychotic or bored and deranged person making a prank call.’
    • ‘During this period many of the friends of the individual affected supposed him to be only very eccentric; while some, who had opportunities of observing him closely, were convinced that he was deranged.’
    • ‘The father got custody of her because the mother is mentally deranged and the police think that this girl is in grave harm.’
    • ‘And if you're deranged enough to forgo the spa treatments and the excuse to not wear real clothes for two days, there's golf, horse riding and mountain-biking on offer nearby.’
    • ‘Also, it could be why he is deranged now, since he obviously isn't on the medication.’
    • ‘The psychologist concluded that the soldier was deranged, and wrote out his discharge from the army.’
    • ‘His unhinged language suggested that persecution mania briefly deranged him.’
    • ‘Well I'm glad that's the only reason you're staring at me like I'm mentally deranged.’
    • ‘Privately, she wondered if they were watching her to see if she would have a breakdown or if she was mentally deranged or something, but she said nothing to that effect.’
    • ‘The boy was from a good family but he was deranged in some way: he wouldn't eat, he quarrelled with everyone, and he refused to go out to work.’
    • ‘And I never dared to ask my parents or teacher for fear of being termed mentally deranged.’
    • ‘There was something demented and deranged about him, a little dark, a little disturbing, that actually scared her.’
    • ‘I was so deranged that I actually considered getting therapy for myself.’
    • ‘You are seriously deranged if you think I'm going to walk thirty miles!’
    • ‘Some of the people in the computer room were glancing at me like I was deranged.’
    • ‘Meanwhile, police based on preliminary investigation ruled out the possibility of him being mentally deranged.’
    • ‘Jordan looked at his wife, as if she was deranged.’
    insane, mad, of unsound mind, out of one's mind, not in one's right mind, disturbed, unbalanced, unhinged, unstable, crazed, demented, irrational, berserk, frenzied, maniac, lunatic, psychopathic, certifiable, raving, raving mad
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    1. 1.1 Cause (something) to act irregularly.
      ‘stress deranges the immune system’
      • ‘As when an individual soldier lost his balance, many flailing and falling soldiers deranged the enemy formation causing a serious decrease in the enemy's own firepower.’
      • ‘Sometimes the stress deranges the managers' senses.’
      • ‘My memory was deranged because of the new program.’
      • ‘It is well known that stress deranges the immune systems of human beings and non-human primates alike.’
      • ‘In addition, antibiotic treatment deranges protective flora and antibiotic resistant microbial strains emerge.’
      • ‘Unforeseen accidents may derange our most profound schemes of policy.’
      • ‘In scoliosis, the anatomy is deranged not only at each vertebral level but also between the convex and concave sides of the curve in the spine.’
      • ‘The group kicked proceedings off, squeezing their way into hormonally deranged teen hearts, with a crisp and punchy pop-punk-pounce.’
      • ‘Several drugs have been shown to derange macrophage functions, bactericidal efficacy and production and secretion of cytokines.’
      • ‘In other patients, the genes preparing neurofilament proteins that support the nerve fibers are deranged.’
      • ‘Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes.’
  • 2archaic Intrude on; disturb.

    ‘I am sorry to have deranged you for so small a matter’
    • ‘From her gauze veiling the young woman spoke:-- "We are sorry to derange you. The guard made a mistake. Pardon!"’
    throw into confusion, throw into disorder, throw into disarray, cause confusion in, cause turmoil in, play havoc with, turn upside-down, make a mess of
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Late 18th century: from French déranger, from Old French desrengier, literally ‘move from orderly rows’.