Definition of derange in English:

derange

verb

[WITH OBJECT]
  • 1Make (someone) insane.

    ‘that business last month must have deranged him a bit’
    • ‘Some of the people in the computer room were glancing at me like I was deranged.’
    • ‘The father got custody of her because the mother is mentally deranged and the police think that this girl is in grave harm.’
    • ‘Maybe it's just some psychotic or bored and deranged person making a prank call.’
    • ‘And I never dared to ask my parents or teacher for fear of being termed mentally deranged.’
    • ‘There was something demented and deranged about him, a little dark, a little disturbing, that actually scared her.’
    • ‘Also, it could be why he is deranged now, since he obviously isn't on the medication.’
    • ‘His unhinged language suggested that persecution mania briefly deranged him.’
    • ‘Jordan looked at his wife, as if she was deranged.’
    • ‘I was so deranged that I actually considered getting therapy for myself.’
    • ‘Meanwhile, police based on preliminary investigation ruled out the possibility of him being mentally deranged.’
    • ‘Well I'm glad that's the only reason you're staring at me like I'm mentally deranged.’
    • ‘However, there is a distinct possibility that I am slightly deranged, so it could just be me that looks at life that way.’
    • ‘No wonder I am deranged and will probably have to spend a big portion of my adult earnings in therapy.’
    • ‘The boy was from a good family but he was deranged in some way: he wouldn't eat, he quarrelled with everyone, and he refused to go out to work.’
    • ‘Imagine going home to your family and friends and being told you were deranged!’
    • ‘And if you're deranged enough to forgo the spa treatments and the excuse to not wear real clothes for two days, there's golf, horse riding and mountain-biking on offer nearby.’
    • ‘During this period many of the friends of the individual affected supposed him to be only very eccentric; while some, who had opportunities of observing him closely, were convinced that he was deranged.’
    • ‘You are seriously deranged if you think I'm going to walk thirty miles!’
    • ‘The psychologist concluded that the soldier was deranged, and wrote out his discharge from the army.’
    • ‘Privately, she wondered if they were watching her to see if she would have a breakdown or if she was mentally deranged or something, but she said nothing to that effect.’
    insane, mad, of unsound mind, out of one's mind, not in one's right mind, disturbed, unbalanced, unhinged, unstable, crazed, demented, irrational, berserk, frenzied, maniac, lunatic, psychopathic, certifiable, raving, raving mad
    non compos mentis
    sectionable
    touched, crazy, cracked, mental
    barmy, barking, barking mad, round the twist
    View synonyms
    1. 1.1Cause (something) to act irregularly.
      ‘stress deranges the immune system’
      • ‘Sometimes the stress deranges the managers' senses.’
      • ‘In addition, antibiotic treatment deranges protective flora and antibiotic resistant microbial strains emerge.’
      • ‘Unforeseen accidents may derange our most profound schemes of policy.’
      • ‘In scoliosis, the anatomy is deranged not only at each vertebral level but also between the convex and concave sides of the curve in the spine.’
      • ‘In other patients, the genes preparing neurofilament proteins that support the nerve fibers are deranged.’
      • ‘My memory was deranged because of the new program.’
      • ‘As when an individual soldier lost his balance, many flailing and falling soldiers deranged the enemy formation causing a serious decrease in the enemy's own firepower.’
      • ‘Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes.’
      • ‘The group kicked proceedings off, squeezing their way into hormonally deranged teen hearts, with a crisp and punchy pop-punk-pounce.’
      • ‘It is well known that stress deranges the immune systems of human beings and non-human primates alike.’
      • ‘Several drugs have been shown to derange macrophage functions, bactericidal efficacy and production and secretion of cytokines.’
  • 2archaic Intrude on; disturb.

    ‘I am sorry to have deranged you for so small a matter’
    • ‘From her gauze veiling the young woman spoke:-- "We are sorry to derange you. The guard made a mistake. Pardon!"’
    throw into confusion, throw into disorder, throw into disarray, cause confusion in, cause turmoil in, play havoc with, derange, turn upside-down, make a mess of
    View synonyms

Origin

Late 18th century: from French déranger, from Old French desrengier, literally move from orderly rows.

Pronunciation:

derange

/dɪˈreɪn(d)ʒ/