One of the mysteries of the English language finally explained.
Easily tired or fatigued; capable of becoming wearied or fatigued; (in later use often) specifically (chiefly humorous) not indefatigable, not tirelessly persistent.
Mid 17th century (in an earlier sense). From post-classical Latin defatigabilis from classical Latin dē- + fatīgāre + -bilis.
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