[mass noun] The failure of an organ (especially the liver or heart) to compensate for the functional overload resulting from disease.
- ‘When liver decompensation occurs and if the patient is a suitable candidate, liver transplantation is the only treatment that extends life.’
- ‘It is hoped that this strategy will prevent the problems associated with long-term volume overload and cardiac decompensation.’
- ‘Patients with chronic liver disease and signs of decompensation should be assessed for transplantation before they become critically ill.’
- ‘We excluded patients with hepatitis B, HIV infection, or hepatic decompensation.’
- ‘The major contributing factor for heart failure decompensation was medication lapses.’
The failure to generate effective psychological coping mechanisms in response to stress, resulting in personality disturbance.