Definition of deafferentation in English:



mass nounBiology
  • The interruption or destruction of the afferent connections of nerve cells, performed especially in animal experiments to demonstrate the spontaneity of locomotor movement.

    • ‘Until 1981, Taub carried out somatosensory deafferentation research with monkeys in which sensation is surgically abolished from the upper extremities.’
    • ‘Despite extensive chest wall deafferentation, the intensity and quality of dyspnea are not altered in patients with spinal cord injury in whom work of breathing is increased by bronchoconstriclion.’
    • ‘It is believed that lateral ankle ligament injury results in not only mechanical instability but also ligamentous deafferentation, contributing to instability.’
    • ‘On the other hand, in REM sleep, the respiratory variability persists even after deafferentation, suggesting that central REM processes underlie the variability.’
    • ‘They argued that neural plasticity allows for a cortical reorganization or remapping of the somatosensory cortex following the deafferentation of neurons.’