Definition of dapsone in English:



  • [mass noun] A sulphur compound with bacteriostatic action, used in the treatment of leprosy.

    • ‘Skin lesions in linear IgA dermatosis and chronic bullous disease of childhood respond rapidly when treated with dapsone or sulfapyridine.’
    • ‘Multidrug treatment with the antibiotic combination rifampicin, dapsone, and clofazimine is highly effective in curing infection, with relapse rates of 1%.’
    • ‘A typical treatment course for Hansen's disease involves multiple drug therapy with dapsone and rifampin for three to five years in patients with tuberculoid leprosy, and for life in patients with lepromatous leprosy.’
    • ‘The sulfone antibiotic dapsone often is recommended, although no prospective trials support its use for bites in humans.’
    • ‘Chemotherapy for leprosy generally includes dapsone, rifampicin and clofazimine, which themselves may affect genetic damage in treated leprosy patients.’
    • ‘Patients will experience prompt relief of lesions within one to two days of initializing treatment with dapsone or sulfapyridine.’
    • ‘The non infectious, paucibacillary form of leprosy is treated with dapsone and rifampicin, and the less common, infectious multibacillary form with a combination of all three drugs.’


1950s: from elements of its alternative systematic name dipara-aminophenyl sulphone.