Definition of cyclic AMP in English:

cyclic AMP


mass nounBiochemistry
  • A cyclic form of adenosine monophosphate (adenylic acid) which plays a major role in controlling many enzyme-catalysed processes in living cells.

    • ‘In the 1970s everything in physiology and medicine was explained by cyclic AMP levels going up or down in cells.’
    • ‘The exact mechanism whereby ISM increases platelet cAMP appears to be that of inhibition of cyclic AMP phosphodiesterase.’
    • ‘Diurnal changes in the plasma levels of cortisol, epinephrine, cyclic AMP and histamine are thought to be the cause of this exacerbation.’
    • ‘By inhibition of certain enzymes, it allows an increase in the concentration of the ‘second messenger’, cyclic AMP, within cells, enhancing in turn the systems which this activates.’
    • ‘The product of adenyl cyclase is cyclic AMP, which quickly degrades in postmortem brain so it cannot be measured.’